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  • NEU1 Antibodies

OriGene

NEU1 Monoclonal Antibody (OTI3D4), TrueMAB™

2 References
View all (25) NEU1 antibodies

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Datasheet
Protocols
Questions & Answers

Cite NEU1 Monoclonal Antibody (OTI3D4), TrueMAB™

  • Antibody Testing Data (9)
NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 9

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NEU1 Antibody (TA801727) in IHC (P)

Immunohistochemical staining of paraffin-embedded human pancreas tissue within the normal limits using anti-NEU1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, TA801727) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NEU1 Antibody in Western Blot (WB)
NEU1 Monoclonal Antibody (OTI3D4), TrueMAB™

Product Details

TA801727

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-

Miscellaneous PubMed (MISC)

-
View 2 publications 2 publications
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OTI3D4

Immunogen

Human recombinant protein fragment corresponding to amino acids 48-315 of human NEU1 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Acetylneuraminyl hydrolase; EC 3.2.1.18; exo-alpha-sialidase; FLJ93471; G9 sialidase; Lysosomal sialidase; N-acetyl-alpha-neuraminidase 1; sialidase 1 (lysosomal sialidase); Sialidase-1

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Gene Aliases: NANH; NEU; NEU1; SIAL1

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UniProt ID: (Human) Q99519

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Entrez Gene ID: (Human) 4758

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Function(s)
exo-alpha-sialidase activity exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity
Process(es)
glycosphingolipid metabolic process ganglioside catabolic process oligosaccharide catabolic process positive regulation of neuron projection development regulation of myoblast proliferation
It has to be done as per old AB suggested Products section.
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