Bioss

NCF1/p47 phox Polyclonal Antibody

Name: NCF1\/p47 phox Polyclonal Antibody
Brand: Bioss
SKU: BS-3886R

View all (23) p47phox antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)

NCF1/p47 phox Antibody in Western Blot (WB)

FIGURE: 1 / 2

NCF1/p47 phox Antibody (BS-3886R) in WB

Mouse bone, lymph node, and spleen lysates probed with Polyclonal Antibody, unconjugated (bs-3886R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C.

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Immunogen image

Immunogen Image NCF1/p47 phox Polyclonal Antibody

Product Details

BS-3886R

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

Immunohistochemistry (Paraffin) (IHC (P))

1:100

Immunocytochemistry (ICC/IF)

1:50-1:200

Flow Cytometry (Flow)

1:20-1:100

ELISA (ELISA)

1:500-1:1,000

Product Specifications

Species Reactivity

Horse, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human NCF1, amino acids 151-250.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

p47phox (NCF1) is required, along with NCF2 and membrane bound cytochrome b558, for activation of the latent NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in the gene can result in granulomatous disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); NCF-1; NCF-47K; neutrop; Neutrophil cytosol factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; P47 phox; p47-phox; phagocyte oxidase 47 kDa; SH3 and PX domain-containing protein 1A

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Gene Aliases: Ncf-1; NCF-47K; NCF1; NCF1A; NOXO2; p47-phox; p47; p47phox; SH3PXD1A

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UniProt ID: (Human) P14598, (Mouse) Q09014

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Entrez Gene ID: (Human) 653361, (Mouse) 17969, (Rat) 114553

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Function(s)

protein binding electron carrier activity superoxide-generating NADPH oxidase activity superoxide-generating NADPH oxidase activator activity SH3 domain binding phosphatidylinositol binding phosphatidylinositol-3,4-bisphosphate binding lipid binding

Process(es)

response to yeast leukocyte mediated cytotoxicity respiratory burst involved in defense response protein targeting to membrane leukotriene metabolic process NADP catabolic process apoptotic process inflammatory response cellular defense response cell proliferation response to bacterium superoxide anion generation defense response to bacterium respiratory burst negative regulation of smooth muscle contraction hydrogen peroxide biosynthetic process defense response to Gram-positive bacterium defense response to fungus oxidation-reduction process neutrophil mediated killing of gram-positive bacterium neutrophil mediated killing of fungus antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent superoxide metabolic process positive regulation of catalytic activity innate immune response cell redox homeostasis vascular endothelial growth factor receptor signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NCF1/p47 phox Polyclonal Antibody

NCF1/p47 phox Antibody (BS-3886R) in WB

Product Details

BS-3886R

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ELISA (ELISA)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

References (0)

Bioinformatics

Performance Guarantee

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