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  • NAE1 Antibodies

OriGene

NAE1 Monoclonal Antibody (OTI1E10), TrueMAB™

View all (25) NAE1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite NAE1 Monoclonal Antibody (OTI1E10), TrueMAB™

  • Antibody Testing Data (4)
NAE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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NAE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 4

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NAE1 Antibody (TA804384) in IHC (P)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-NAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA804384) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NAE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NAE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NAE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NAE1 Antibody in Western Blot (WB)
NAE1 Monoclonal Antibody (OTI1E10), TrueMAB™

Product Details

TA804384

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1E10

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-274 of human NAE1 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: amyloid beta precursor protein binding protein 1, 59kDa; Amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; Amyloid protein-binding protein 1; APP-BP1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8-activating enzyme E1 subunit; Proto-oncogene protein 1; protooncogene protein 1

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Gene Aliases: A-116A10.1; APPBP1; HPP1; NAE1; ula-1

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UniProt ID: (Human) Q13564

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Entrez Gene ID: (Human) 8883

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Function(s)
protein binding NEDD8 activating enzyme activity ubiquitin protein ligase binding protein heterodimerization activity
Process(es)
signal transduction mitotic DNA replication checkpoint regulation of apoptotic process regulation of neuron apoptotic process protein neddylation neuron apoptotic process
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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