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  • MYL2 Antibodies

Invitrogen

MYL2 Polyclonal Antibody

View all (27) MYL2 antibodies

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Datasheet
Protocols
Questions & Answers

Cite MYL2 Polyclonal Antibody

  • Antibody Testing Data (5)
MYL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MYL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MYL2 Antibody (PA5-78401) in IHC (P)

Immunohistochemistry (Paraffin) analysis of MYL2 was performed in paraffin-embedded mouse muscle tissue using MYL2 Polyclonal Antibody (Product # PA5-78401) at a dilution of 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MYL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MYL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MYL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MYL2 Antibody in Western Blot (WB)
MYL2 Antibody in Western Blot (WB)
MYL2 Polyclonal Antibody

Product Details

PA5-78401

Applications
Tested Dilution
Publications

Western Blot (WB)

1:5,000-1:20,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Myosin Light Chain 2 (MLC-2v). The exact sequence is proprietary.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.1M tris glycine, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2736184

Product Specific Information

Positive Control: Mouse heart

Predicted Reactivity: Human (100%), Rat (100%), Dog (100%)

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cardiac myosin light chain 2; cardiac myosin light chain-2; cardiac ventricular myosin light chain 2; DKFZp779C0562; MLC-2; MLC-2s/v; MLC-2v; Myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2v; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; myosin light chain-2; Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; Ventricular myosin light chain 2; ventricular myosin regulatory light chain

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Gene Aliases: CMH10; MLC-2; MLC-2s/v; MLC-2v; MLC2; Mlc2v; MYL2; Mylpc

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UniProt ID: (Human) P10916, (Rat) P08733, (Mouse) P51667

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Entrez Gene ID: (Human) 4633, (Rat) 363925, (Mouse) 17906

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Function(s)
actin monomer binding calcium ion binding protein binding structural constituent of muscle myosin heavy chain binding metal ion binding
Process(es)
regulation of the force of heart contraction regulation of striated muscle contraction heart development post-embryonic development muscle filament sliding negative regulation of cell growth muscle cell fate specification muscle fiber development cardiac myofibril assembly ventricular cardiac muscle tissue morphogenesis heart contraction cardiac muscle contraction positive regulation of the force of heart contraction heart morphogenesis
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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