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Invitrogen
MUSK Recombinant Rabbit Monoclonal Antibody (PSH05-68)
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Product Details
MA5-52463
Host/Isotype
Expression System
Class
Type
Clone
Immunogen
Conjugate
Storage conditions
Shipping conditions
RRID
Product Specific Information
Positive Control: Mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue.
Sequence Similarities: 100% Mouse/Rat.
Subcellular Location: Postsynaptic cell membrane.
Predicted band size: 97 kDa.
Target Information
MUSK plays an important and selective role in many aspects of skeletal muscle development and function through the initial step of postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn. Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells. Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor. MuSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintenance of the neuromuscular junction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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