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  • MTHFD1L Antibodies

Proteintech

MTHFD1L Monoclonal Antibody (1G1F2)

View all (11) MTHFD1L antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite MTHFD1L Monoclonal Antibody (1G1F2)

  • Antibody Testing Data (4)
MTHFD1L Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MTHFD1L Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 4

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MTHFD1L Antibody (68321-1-IG) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 68321-1-Ig (MTHFD1L antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MTHFD1L Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MTHFD1L Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MTHFD1L Antibody in Western Blot (WB)
MTHFD1L Antibody in Western Blot (WB)
MTHFD1L Monoclonal Antibody (1G1F2)

Product Details

68321-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:5,000-1:50,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:250-1:1,000
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Rabbit, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

1G1F2

Immunogen

Recombinant protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Protein A

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: GRMVVASDKS GQPVTADDLG VTGALTVLMK DAIKPNLMQT LEGTPVFVHA GPFANIAHGN SSVLADKIAL KLVGEEGFVV TEAGFGADIG MEKFFNIKCR ASGLVPNVVV LVATVRALKM HGGGPSVTAG VPLKKEYTEE NIQLVADGCC NLQKQIQITQ LFGVPVVVAL NVFKTDTRAE IDLVCELAKR AGAFDAVPCY HWSVGGKGSV DLARAVREAA SKRSRFQFLY DVQVPIVDKI RTIAQAVYGA KDIELSPEAQ AKIDRYTQQG FGNLPICMAK THLSLSHQPD KKGVPRDFIL PISDVRASIG AGFIYPLVGT MSTMPGLPTR PCFYDIDLDT ETEQVKGLF

Target Information

One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 10-formyl-THF synthetase; Formyltetrahydrofolate synthetase; formyltetrahydrofolate synthetase domain containing 1; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; Monofunctional C1-tetrahydrofolate synthase, mitochondrial

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Gene Aliases: dJ292B18.2; FTHFSDC1; MTC1THFS; MTHFD1L

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UniProt ID: (Human) Q6UB35

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Entrez Gene ID: (Rabbit) 100343064, (Human) 25902, (Rat) 361472

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Function(s)
formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NADP+) activity ATP binding protein homodimerization activity molecular_function
Process(es)
one-carbon metabolic process folic acid-containing compound metabolic process biological_process folic acid-containing compound biosynthetic process formate metabolic process tetrahydrofolate metabolic process oxidation-reduction process neural tube closure tetrahydrofolate interconversion folic acid metabolic process embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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