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  • Primary Antibodies ›
  • MRP2 Antibodies

Invitrogen

MRP2 Monoclonal Antibody (M2I-4)

View all (24) MRP2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite MRP2 Monoclonal Antibody (M2I-4)

MRP2 Monoclonal Antibody (M2I-4)

Product Details

MA1-26535

Applications
Tested Dilution
Publications

Western Blot (WB)

1:20-1:50
-

Immunohistochemistry (Frozen) (IHC (F))

1:20
-

Immunocytochemistry (ICC/IF)

1:20-1:50
-

Flow Cytometry (Flow)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Clone

M2I-4

Immunogen

Bacterial fusion protein of human MRP 2 containing amino acids of 215-310.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

purified

Storage buffer

PBS with 1% BSA

Contains

0.1% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_794961

Product Specific Information

MA1-26535 detects multidrug resistance associated protein 2 from human samples.

Target Information

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ATP-binding cassette sub-family C member 2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; Human MRP2; KIAA1010; Multidrug resistance-associated protein 2

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Gene Aliases: ABC30; ABCC2; CMOAT; CMOAT1; CMRP; DJS; MRP2

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UniProt ID: (Human) Q92887

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Entrez Gene ID: (Human) 1244

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Function(s)
protein binding ATP binding organic anion transmembrane transporter activity bilirubin transmembrane transporter activity protein domain specific binding ATPase activity, coupled to transmembrane movement of substances anion transmembrane-transporting ATPase activity
Process(es)
transport drug transmembrane transport response to oxidative stress response to heat bilirubin transport prostaglandin transport cellular chloride ion homeostasis response to methotrexate response to estrogen response to arsenic-containing substance response to steroid hormone transmembrane transport thyroid hormone transport anion transmembrane transport
It has to be done as per old AB suggested Products section.
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