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  • MRP2 Antibodies

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MRP2 Polyclonal Antibody

View all (24) MRP2 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite MRP2 Polyclonal Antibody

  • Antibody Testing Data (4)
MRP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MRP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MRP2 Antibody (BS-1092R) in IHC (P)

Formalin-fixed and paraffin-embedded human liver carcinoma labeled with Anti-MRP2 Polyclonal Antibody, Unconjugated(bs-1092R) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG,PE conjugated(bs-0295G-PE)used at 1:200 dilution for 40 minutes at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MRP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MRP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MRP2 Antibody in Western Blot (WB)
MRP2 Antibody in Western Blot (WB)
MRP2 Polyclonal Antibody

Product Details

BS-1092R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human MRP2, amino acids 485-615.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ATP-binding cassette sub-family C member 2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; calicular multispecific organic anion transporter; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; Human MRP2; KIAA1010; multidrug resistance associated protein 2; multidrug resistance protein 2; Multidrug resistance-associated protein 2

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Gene Aliases: ABC30; ABCC2; AI173996; CMOAT; CMOAT1; CMRP; DJS; MRP2

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UniProt ID: (Human) Q92887, (Rat) Q63120, (Mouse) Q8VI47

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Entrez Gene ID: (Human) 1244, (Rat) 25303, (Mouse) 12780

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Function(s)
protein binding ATP binding organic anion transmembrane transporter activity bilirubin transmembrane transporter activity protein domain specific binding ATPase activity, coupled to transmembrane movement of substances anion transmembrane-transporting ATPase activity
Process(es)
drug transmembrane transport response to oxidative stress metabolic process response to heat organic anion transport prostaglandin transport cellular chloride ion homeostasis response to methotrexate response to drug response to estrogen response to arsenic-containing substance response to steroid hormone thyroid hormone transport transport bilirubin transport transmembrane transport anion transmembrane transport
It has to be done as per old AB suggested Products section.
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