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  • MMP11 Antibodies

OriGene

MMP11 Monoclonal Antibody (OTI3E10), TrueMAB™

View all (16) MMP11 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite MMP11 Monoclonal Antibody (OTI3E10), TrueMAB™

  • Antibody Testing Data (2)
MMP11 Antibody in Western Blot (WB)
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MMP11 Antibody in Western Blot (WB)
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MMP11 Antibody (CF812659) in WB

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP11 (RC209223, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP11. Positive lysates LY416967 (100 µg) and LC416967 (20 µg) can be purchased separately from OriGene. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MMP11 Antibody in Western Blot (WB)
MMP11 Antibody in Western Blot (WB)
MMP11 Monoclonal Antibody (OTI3E10), TrueMAB™

Product Details

CF812659

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI3E10

Immunogen

Human recombinant protein fragment corresponding to amino acids 239-488 of human MMP11 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: matrix metallo protease; matrix metallopeptidase 11 (stromelysin 3); Matrix metalloproteinase-11; MMP; MMP-11; MMPs; SL-3; stromelysin III; Stromelysin-3

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Gene Aliases: MMP11; SL-3; ST3; STMY3

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UniProt ID: (Human) P24347

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Entrez Gene ID: (Human) 4320

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Function(s)
metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding zinc ion binding
Process(es)
proteolysis multicellular organism development extracellular matrix disassembly collagen fibril organization collagen catabolic process negative regulation of fat cell differentiation basement membrane organization
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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