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  • Primary Antibodies ›
  • CCL7 (MCP3) Antibodies

Invitrogen

MCP-3 Monoclonal Antibody (36320)

View all (20) CCL7 (MCP3) antibodies

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Datasheet
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Questions & Answers

Cite MCP-3 Monoclonal Antibody (36320)

MCP-3 Monoclonal Antibody (36320)

Product Details

MA5-23733

Applications
Tested Dilution
Publications

Western Blot (WB)

1 µg/mL
-

Flow Cytometry (Flow)

2.5 µg per million cells
-

ELISA (ELISA)

0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)
-

Neutralization (Neu)

1.5-4.5 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

36320

Immunogen

E. coli-derived recombinant human CCL7/MCP-3/MARC Gln34-109
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608255

Product Specific Information

In ELISAs, this antibody does not cross-react with recombinant human (rh) CCL2/MCP-1, rhCCL8/MCP-2, or rhCCL13/MCP-4.

Reconstitute at 0.5 mg/mL in sterile PBS.

Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C-C motif chemokine 7; chemokine (C-C motif) ligand 7; H-MCP-3; MCP-3; MGC138463; MGC138465; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; NC28; RP23-350G1.4; small inducible cytokine A7 (monocyte chemotactic protein 3); Small-inducible cytokine A7

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Gene Aliases: CCL7; FIC; MARC; MCP-3; MCP3; NC28; SCYA6; SCYA7

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UniProt ID: (Human) P80098

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Entrez Gene ID: (Human) 6354

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Function(s)
protein binding chemokine activity heparin binding CCR1 chemokine receptor binding CCR2 chemokine receptor binding
Process(es)
monocyte chemotaxis cellular calcium ion homeostasis chemotaxis inflammatory response cytoskeleton organization signal transduction G-protein coupled receptor signaling pathway cell-cell signaling regulation of cell shape response to gamma radiation positive regulation of cell migration neutrophil chemotaxis positive regulation of GTPase activity eosinophil chemotaxis positive regulation of inflammatory response chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to ethanol positive regulation of natural killer cell chemotaxis
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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