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  • MARCKS Antibodies

Invitrogen

MARCKS Polyclonal Antibody

View all (32) MARCKS antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite MARCKS Polyclonal Antibody

  • Antibody Testing Data (2)
MARCKS Antibody in Immunocytochemistry (ICC/IF)
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MARCKS Antibody in Immunocytochemistry (ICC/IF)
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MARCKS Antibody (PA5-84764) in ICC/IF

Immunofluorecent analysis of MARCKS in human cell line U-251 MG using MARCKS Polyclonal Antibody (Product # PA5-84764). Staining shows localization to plasma membrane and endoplasmic reticulum. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MARCKS Antibody in Immunocytochemistry (ICC/IF)
MARCKS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MARCKS Polyclonal Antibody

Product Details

PA5-84764

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:2,500-1:5,000
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MARCKS. Recombinant protein control fragment (Product #RP-106359).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791914

Product Specific Information

Immunogen sequence: DPQEAKPQEA AVAPEKPPAS DETKAAEEPS KVEEK

Target Information

MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 80K-L protein; FLJ14368; FLJ90045; MARCKS; MARCS; Myristoylated alanine-rich C-kinase substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; Protein kinase C substrate, 80 kDa protein, light chain

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Gene Aliases: 80K-L; MACS; MARCKS; PKCSL; PRKCSL

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UniProt ID: (Human) P29966

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Entrez Gene ID: (Human) 4082

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Function(s)
phosphatidylserine binding protein kinase C binding calmodulin binding actin filament binding
Process(es)
ventricular cardiac muscle tissue development intracellular protein transport actin filament organization brain development activation of phospholipase D activity cell-substrate adhesion regulation of insulin secretion positive regulation of dendritic spine morphogenesis positive regulation of protein kinase C activity positive regulation of glucose import in response to insulin stimulus
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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