Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • MAN1 Antibodies

Invitrogen

MAN1 Monoclonal Antibody (OTI3H1)

View all (17) MAN1 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite MAN1 Monoclonal Antibody (OTI3H1)

  • Antibody Testing Data (4)
MAN1 Antibody in Immunocytochemistry (ICC/IF)
Group 53 Created with Sketch.
MAN1 Antibody in Immunocytochemistry (ICC/IF)
Group 53 Created with Sketch.

FIGURE: 1 / 4

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

MAN1 Antibody (MA5-25020) in ICC/IF

Immunofluorescent analysis of LEMD3 in COS7 cells. Cells were transfected with a plasmid overexpressing LEMD3 and probed with a LEMD3 monoclonal antibody (Product # MA5-25020). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

MAN1 Antibody in Immunocytochemistry (ICC/IF)
MAN1 Antibody in Western Blot (WB)
MAN1 Antibody in Western Blot (WB)
MAN1 Antibody in Western Blot (WB)
MAN1 Monoclonal Antibody (OTI3H1)

Product Details

MA5-25020

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunocytochemistry (ICC/IF)

1:100
-

Flow Cytometry (Flow)

1:100
-

Immunoprecipitation (IP)

2-4 µg/mL
-
Product Specifications

Species Reactivity

Dog, Human, Non-human primate, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI3H1

Immunogen

Full length human recombinant protein of LEMD3 produced in HEK293T cell
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2723351

Target Information

Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Inner nuclear membrane protein Man1; integral inner nuclear membrane protein; LEM domain containing 3; LEM domain-containing protein 3

View more View less

Gene Aliases: LEMD3; MAN1; RGD1561001

View more View less

UniProt ID: (Human) Q9Y2U8

View more View less

Entrez Gene ID: (Dog) 608380, (Human) 23592, (Rat) 680066

View more View less

Function(s)
nucleotide binding DNA binding protein binding
Process(es)
angiogenesis blood vessel endothelial cell migration involved in intussusceptive angiogenesis nucleus organization negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway negative regulation of activin receptor signaling pathway skeletal muscle cell differentiation regulation of cell cycle regulation of extracellular matrix organization
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-649bfd9c6b-jlsz7:80/100.66.128.142:80.
git-commit: 6001d82975f0049f9efc09ec70b1b2d89229eeb3
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.2-2025.09.39-1.0