Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • Lamin A/C Antibodies

Invitrogen

Lamin A/C Monoclonal Antibody (4E7)

View all (48) Lamin A/C antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Lamin A/C Monoclonal Antibody (4E7)

  • Antibody Testing Data (3)
Lamin A/C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.
Lamin A/C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.

FIGURE: 1 / 3

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

Lamin A/C Antibody (MA5-15882) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human striated muscle tissues using LMNA monoclonal antibody (Product # MA5-15882) followed with DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

Lamin A/C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Lamin A/C Antibody in Western Blot (WB)
Lamin A/C Antibody in Western Blot (WB)

Product Details

MA5-15882

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000
-

ELISA (ELISA)

1:10,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

4E7

Immunogen

Purified recombinant fragment of human LMNA expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11152687

Product Specific Information

MA5-15882 targets LMNA in indirect ELISA, IHC and WB applications and shows reactivity with Human, mouse, and Rat samples.

The MA5-15882 immunogen is purified recombinant fragment of human LMNA expressed in E. Coli.

MA5-15882 detects LMNA which has a predicted molecular weight of approximately 74kDa.

Target Information

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: 70 kDa lamin; lamin A; Lamin A+C mutant; lamin a-c; lamin A/C-like 1; Lamin AC; lamin C; lamin C2; lamin-A/C; mutant 453W; Mutant lamin A/C; Prelamin-A/C; progerin mutant; renal carcinoma antigen NY-REN-32; RP11-54H19.1

View more View less

Gene Aliases: CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; PRO1

View more View less

UniProt ID: (Human) P02545, (Mouse) P48678

View more View less

Entrez Gene ID: (Human) 4000, (Mouse) 16905, (Rat) 60374

View more View less

Function(s)
structural molecule activity protein binding protein phosphatase 1 binding
Process(es)
nucleus organization nuclear envelope organization muscle organ development establishment of cell polarity regulation of cell migration establishment or maintenance of microtubule cytoskeleton polarity protein localization to nucleus sterol regulatory element binding protein import into nucleus ventricular cardiac muscle cell development negative regulation of release of cytochrome c from mitochondria positive regulation of cell aging regulation of protein localization to nucleus negative regulation of extrinsic apoptotic signaling pathway mitotic nuclear envelope disassembly mitotic nuclear envelope reassembly spermatogenesis response to mechanical stimulus IRE1-mediated unfolded protein response positive regulation of osteoblast differentiation cellular response to hypoxia negative regulation of adipose tissue development
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-649bfd9c6b-jlsz7:80/100.66.128.142:80.
git-commit: 6001d82975f0049f9efc09ec70b1b2d89229eeb3
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.2-2025.09.39-1.0