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  • Primary Antibodies ›
  • TNF beta Antibodies

Abnova

LTA Monoclonal Antibody (1C12)

View all (51) TNF beta antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite LTA Monoclonal Antibody (1C12)

LTA Monoclonal Antibody (1C12)

Product Details

H00004049-M16

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

ELISA (ELISA)

10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

1C12

Immunogen

Recombinant Flag/His fusion protein corresponding to amino acids 58-205 of human LTA.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: HSTLKPAAHL IGDPSKQNSL LWRANTDRAF LQDGFSLSNN SLLVPTSGIY FVYSQVVFSG KAYSPKATSS PLYLAHEVQL FSSQYPFHVP LLSSQKMVYP GLQEPWLHSM YHGAAFQLTQ GDQLSTHTDG IPHLVLSPST VFFGAFAL

Target Information

TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DAMA-25N12.13; LT-alpha; Lymphotoxin-alpha; TNF b; TNF beta; TNF superfamily, member 1; TNF β; TNF-beta; TNFbeta; TNFβ; tumor necrosis factor beta; tumor necrosis factor ligand 1E; Tumor necrosis factor ligand superfamily member 1

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Gene Aliases: LT; LTA; TNFB; TNFSF1; TNLG1E

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UniProt ID: (Human) P01374

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Entrez Gene ID: (Human) 4049

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Function(s)
receptor binding cytokine activity tumor necrosis factor receptor binding
Process(es)
response to hypoxia positive regulation of chronic inflammatory response to antigenic stimulus positive regulation of humoral immune response mediated by circulating immunoglobulin apoptotic process humoral immune response signal transduction cell-cell signaling response to nutrient response to lipopolysaccharide positive regulation of interferon-gamma production tumor necrosis factor-mediated signaling pathway response to drug positive regulation of apoptotic process negative regulation of growth of symbiont in host negative regulation of fibroblast proliferation lymph node development defense response to Gram-positive bacterium positive regulation of glial cell proliferation
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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