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OriGene

LPL Monoclonal Antibody (OTI4F6), TrueMAB™

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite LPL Monoclonal Antibody (OTI4F6), TrueMAB™

  • Antibody Testing Data (3)
LPL Antibody in Immunocytochemistry (ICC/IF)
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LPL Antibody in Immunocytochemistry (ICC/IF)
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LPL Antibody (CF503792) in ICC/IF

Anti-LPL mouse monoclonal antibody (TA503792) Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LPL(RC203766). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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LPL Antibody in Immunocytochemistry (ICC/IF)
LPL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
LPL Antibody in Western Blot (WB)
LPL Monoclonal Antibody (OTI4F6), TrueMAB™

Product Details

CF503792

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI4F6

Immunogen

Human recombinant protein fragment corresponding to amino acids 28-475 of human LPL produced in HEK293T cell
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: alpha lipase; Lipoprotein lipase; LPL; Phospholipase A1

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Gene Aliases: HDLCQ11; LIPD; LPL

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UniProt ID: (Human) P06858

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Entrez Gene ID: (Human) 4023

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Function(s)
lipoprotein lipase activity phospholipase activity triglyceride lipase activity receptor binding protein binding heparin binding triglyceride binding apolipoprotein binding
Process(es)
retinoid metabolic process fatty acid biosynthetic process triglyceride metabolic process phospholipid metabolic process response to cold response to glucose positive regulation of macrophage derived foam cell differentiation positive regulation of cholesterol storage positive regulation of sequestering of triglyceride triglyceride biosynthetic process triglyceride catabolic process chylomicron remodeling very-low-density lipoprotein particle remodeling lipoprotein metabolic process response to drug cholesterol homeostasis positive regulation of inflammatory response triglyceride homeostasis positive regulation of chemokine secretion
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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