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  • LOXL2 Antibodies

Invitrogen

LOXL2 Recombinant Rabbit Monoclonal Antibody (7H25L21)

Advanced Verification
1 Published Figure
1 Reference
View all (29) LOXL2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite LOXL2 Recombinant Rabbit Monoclonal Antibody (7H25L21)

  • Antibody Testing Data (3)
  • Published Figures (1)
  • Advanced Verification (1)
LOXL2 Antibody in Immunocytochemistry (ICC/IF)
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LOXL2 Antibody in Immunocytochemistry (ICC/IF)
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LOXL2 Antibody (702694) in ICC/IF

For immunofluorescence analysis, HeLa cells were fixed and permeabilized for detection of endogenous LOXL2 using Anti-LOXL2 Recombinant Rabbit Monoclonal Antibody (Product # 702694, 5 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of LOXL2 protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S3693... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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LOXL2 Antibody in Immunocytochemistry (ICC/IF)
LOXL2 Antibody in Western Blot (WB)
LOXL2 Antibody in Western Blot (WB)
LOXL2 Antibody in Immunocytochemistry (ICC/IF)
LOXL2 Antibody
LOXL2 Recombinant Rabbit Monoclonal Antibody (7H25L21)

Product Details

702694

Applications
Tested Dilution
Publications

Western Blot (WB)

2.5 µg/mL
-

Immunocytochemistry (ICC/IF)

5 µg/mL
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Monoclonal

Type

Antibody

Clone

7H25L21

Immunogen

Peptides corresponding to human LOXL2 [1) aa28-aa45 2) aa239-aa258]
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2716885

Product Specific Information

This antibody is predicted to react with Monkey, Bovine, Cat

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Lysyl oxidase homolog 2; lysyl oxidase related 2; lysyl oxidase-like 2 delta e13; lysyl oxidase-like 2 protein; Lysyl oxidase-like protein 2; Lysyl oxidase-related protein 2; Lysyl oxidase-related protein WS9-14

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Gene Aliases: LOR2; LOXL2; WS9-14

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UniProt ID: (Human) Q9Y4K0

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Entrez Gene ID: (Human) 4017

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Function(s)
chromatin binding transcription corepressor activity protein-lysine 6-oxidase activity scavenger receptor activity copper ion binding protein binding electron carrier activity methylated histone binding oligosaccharide binding
Process(es)
response to hypoxia epithelial to mesenchymal transition endothelial cell proliferation sprouting angiogenesis transcription, DNA-templated cellular protein modification process receptor-mediated endocytosis cell adhesion aging histone modification protein deamination collagen fibril organization positive regulation of chondrocyte differentiation endothelial cell migration negative regulation of transcription, DNA-templated response to copper ion oxidation-reduction process
It has to be done as per old AB suggested Products section.
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