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Invitrogen
LIPC Polyclonal Antibody
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FIGURE: 1 / 2
LIPC Antibody (PA5-78040) in IHC (P)
Product Details
PA5-78040
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Storage conditions
Shipping conditions
RRID
Product Specific Information
Positive Control: HepG2
Predicted Reactivity: Mouse (81%), Dog (82%), Pig (80%), Rabbit (82%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The Lipase family belongs to one of the most robust genetic superfamilies found in living organisms that includes esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Balancing the composition and the transport of lipoproteins in human plasma is essential for normal body function and is mediated in part by Hepatic Lipase, also known as HL or LIPC. Rare deficiencies in Hepatic Lipase have been identified in humans which lead to pathologic levels of circulating lipoprotein particles; this condition is associated with coronary artery disease (CAD). Hepatic Lipase is regulated by thyroid hormones and has a dual function as a triglyceride hydrolase and a ligand/bridging factor for receptor-mediated lipoprotein uptake. Hepatic Lipase localizes to the endothelial surfaces of extrahepatic tissues.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: hepatic lipase; Hepatic triacylglycerol lipase; HL; Lipase member C; lipase, hepatic; Lysophospholipase; Phospholipase A1; Triacylglycerol lipase
Gene Aliases: HDLCQ12; HL; HTGL; LIPC; LIPH
UniProt ID: (Human) P11150
Entrez Gene ID: (Human) 3990
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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