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  • LIAS Antibodies

Proteintech

LIAS Polyclonal Antibody

17 References
View all (10) LIAS antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite LIAS Polyclonal Antibody

  • Antibody Testing Data (5)
LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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LIAS Antibody (11577-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using (Product # 11577-1-AP) (LIAS antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
LIAS Antibody in Western Blot (WB)
LIAS Antibody in Western Blot (WB)
LIAS Polyclonal Antibody

Product Details

11577-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 14 publications 14 publications

Immunohistochemistry (IHC)

-
View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LIAS Fusion Protein Ag2162 (1-372 aa encoded by BC023635)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSLRCGDAA RTLGPRVFGR YFCSPVRPLS SLPDKKKELL QNGPDLQDFV SGDLADRSTW DEYKGNLKRQ KGERLRLPPW LKTEIPMGKN YNKLKNTLRN LNLHTVCEEA RCPNIGECWG GGEYATATAT IMLMGDTCTR GCRFCSVKTA RNPPPLDASE PYNTAKAIAE WGLDYVVLTS VDRDDMPDGG AEHIAKTVSY LKERNPKILV ECLTPDFRGD LKAIEKVALS GLDVYAHNVE TVPELQSKVR DPRVNFDQSL RVLKHAKKVQ PDVISKTSIM LGLGENDEQV YATMKALREA DVDCLTLGQY MQPTRRHLKV EEYITPEKFK YWEKVGNELG FHYTASGPLV RSSYKAGEFF LKNLVAKRKT KDL (1-372 aa encoded by BC023635)

Target Information

LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: LIAS; lip-syn; lip-syn {ECO:0000255|HAMAP-Rule:MF_03123}; Lipoate synthase; lipoate synthase {ECO:0000255|HAMAP-Rule:MF_03123}; Lipoic acid synthase; lipoic acid synthase {ECO:0000255|HAMAP-Rule:MF_03123}; Lipoyl synthase, mitochondrial; lipoyl synthase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03123}; LS; LS {ECO:0000255|HAMAP-Rule:MF_03123}; MGC23245

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Gene Aliases: 2900022L22Rik; 4933425M12Rik; 7a5ex; C77512; HGCLAS; HUSSY-01; LAS; LIAS; LIP1; LS; mLip1; PDHLD

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UniProt ID: (Human) O43766, (Rat) Q5XIH4, (Mouse) Q99M04

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Entrez Gene ID: (Human) 11019, (Rat) 305348, (Mouse) 79464

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Function(s)
lipoate synthase activity metal ion binding 4 iron, 4 sulfur cluster binding molecular_function catalytic activity transferase activity iron-sulfur cluster binding
Process(es)
neural tube closure inflammatory response response to oxidative stress biological_process lipoate biosynthetic process protein lipoylation response to lipopolysaccharide glyoxylate metabolic process
It has to be done as per old AB suggested Products section.
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