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  • Galectin 3 Antibodies

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LGALS3 Monoclonal Antibody (OTI1A2), Biotin, TrueMAB™

View all (131) Galectin 3 antibodies

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Cite LGALS3 Monoclonal Antibody (OTI1A2), Biotin, TrueMAB™

  • Antibody Testing Data (1)
LGALS3 Antibody in Luminex (LUM)
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LGALS3 Antibody in Luminex (LUM)
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LGALS3 Antibody (TA700458) in LUM

LGALS33 Luminex ELISA with 1A4 Capture (TA600458) and 1A2 Detection (TA700458) Antibodies. Substrate used: Recombinant Human LGALS33 (TP308785) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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LGALS3 Antibody in Luminex (LUM)
LGALS3 Monoclonal Antibody (OTI1A2), Biotin, TrueMAB™

Product Details

TA700458

Applications
Tested Dilution
Publications

ELISA (ELISA)

1:250-1:1,000
-

Luminex (LUM)

Assay-Dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1A2

Immunogen

Full length human recombinant protein of human LGALS3 produced in HEK293T cell.
View immunogen

Conjugate

Biotin Biotin Biotin
  • Unconjugated
  • Request custom conjugation

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 10mg/mL BSA, 50% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 35 kDa lectin; advanced glycation end-product receptor 3; Carbohydrate-binding protein 35; CBP 35; CBP-30; Gal-3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin-3; Galectin3; IgE-binding protein; L-29; L-31; Laminin-binding protein; Lectin L-29; lectin, galactoside-binding, soluble, 3; MAC-2 antigen

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Gene Aliases: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; LGALS3; MAC2

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UniProt ID: (Human) P17931

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Entrez Gene ID: (Human) 3958

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Function(s)
protein binding IgE binding carbohydrate binding chemoattractant activity laminin binding poly(A) RNA binding
Process(es)
monocyte chemotaxis mRNA processing RNA splicing neutrophil chemotaxis epithelial cell differentiation regulation of T cell proliferation innate immune response negative regulation of endocytosis eosinophil chemotaxis macrophage chemotaxis negative regulation of T cell receptor signaling pathway positive chemotaxis regulation of T cell apoptotic process mononuclear cell migration positive regulation of mononuclear cell migration positive regulation of calcium ion import regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of immunological synapse formation negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of dendritic cell differentiation negative regulation of extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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