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LEPREL2 Monoclonal Antibody (1F6F3)

View all (7) LEPREL2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite LEPREL2 Monoclonal Antibody (1F6F3)

  • Antibody Testing Data (3)
LEPREL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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LEPREL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 3

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LEPREL2 Antibody (68299-1-IG) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse ovary tissue slide using 68299-1-Ig (LEPREL2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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LEPREL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
LEPREL2 Antibody in Western Blot (WB)
LEPREL2 Antibody in Western Blot (WB)
LEPREL2 Monoclonal Antibody (1F6F3)

Product Details

68299-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:5,000-1:50,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1F6F3

Immunogen

Recombinant protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Protein G

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: RALNQYQAQL GEPRPGLGPR EDIQRFILRS LGEKRQLYYA MEHLGTSFKD PDPWTPAALI PEALREKLRE DQEKRPWDHE PVKPKPLTYW KDVLLLEGVT LTQDSRQLNG SERAVLDGLL TPAECGVLLQ LAKDAAGAGA RSGYRGRRSP HTPHERFEGL TVLKAAQLAR AGTVGSQGAK LLLEVSERVR TLTQAYFSPE RPLHLSFTHL VCRSAIEGEQ EQRMDLSHPV HADNCVLDPD TGECWREPPA YTYRDYSGLL YLNDDFQGGD LFFTEPNALT VTARVRPRCG RLVAFSSGVE NPHGVWAVTR GRRCALALWH TWAPEHREQE WIEAKELLQE SQEEEEEEEE EMPSKDPSPE PPSRRHQRVQ DKTGRAPRVR EEL

Target Information

The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: gene rich cluster, B; leprecan-like 2; Leprecan-like protein 2; procollagen-proline 3-dioxygenase; Prolyl 3-hydroxylase 3; Protein B

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Gene Aliases: GRCB; HSU47926; LEPREL2; P3H3

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UniProt ID: (Human) Q8IVL6

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Entrez Gene ID: (Human) 10536, (Rat) 297595

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Function(s)
iron ion binding procollagen-proline 3-dioxygenase activity L-ascorbic acid binding molecular_function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Process(es)
negative regulation of cell proliferation peptidyl-proline hydroxylation oxidation-reduction process biological_process
It has to be done as per old AB suggested Products section.
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