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Invitrogen
LEPREL1 Polyclonal Antibody
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Product Details
PA5-52480
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Product Specific Information
Immunogen sequence: LHYDYLQFAY YRVGEYVKAL ECAKAYLLCH PDDEDVLDNV DYYESLLDDS IDPASIEARE DLTMFVKRHK LESELIKSAA EGLGFSYTEP NYWIRYGGRQ DENRVPSGVN VEGAEVHGFS MGKKLSPKID RDLREGGPLL Y
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
Target Information
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: leprecan-like 1; Leprecan-like protein 1; Myxoid liposarcoma-associated protein 4; procollagen-proline 3-dioxygenase 2; Prolyl 3-hydroxylase 2; prolyl 3-hydroxylase 3
Gene Aliases: LEPREL1; MCVD; MLAT4; P3H2
UniProt ID: (Human) Q8IVL5, (Rat) Q4KLM6
Entrez Gene ID: (Human) 55214, (Rat) 288016
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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