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  • Primary Antibodies ›
  • LEPRE1 Antibodies

Abnova

LEPRE1 Monoclonal Antibody (3A4)

View all (26) LEPRE1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite LEPRE1 Monoclonal Antibody (3A4)

Product Details

H00064175-M02

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

ELISA (ELISA)

10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

3A4

Immunogen

LEPRE1 (AAH15309, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: DPRVREVMNQ NLAYYAAMLG EEHTRSIGPR ESAKEYRQRS LLEKELLFFA YDVFGIPFVD PDSWTPEEVI PKRLQEKQKS ERETAVRISQ EIGNLMKEIE

Target Information

Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro- Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Growth suppressor 1; leprecan; Leprecan-1; leucine proline-enriched proteoglycan (leprecan) 1; Leucine- and proline-enriched proteoglycan 1; procollagen-proline 3-dioxygenase; Prolyl 3-hydroxylase 1

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Gene Aliases: GROS1; LEPRE1; OI8; P3H1; PSEC0109

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UniProt ID: (Human) Q32P28

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Entrez Gene ID: (Human) 64175

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Function(s)
molecular_function iron ion binding collagen binding procollagen-proline 3-dioxygenase activity L-ascorbic acid binding protein complex binding
Process(es)
protein folding negative regulation of cell proliferation protein hydroxylation peptidyl-proline hydroxylation collagen metabolic process regulation of protein secretion protein stabilization oxidation-reduction process bone development chaperone-mediated protein folding negative regulation of post-translational protein modification
It has to be done as per old AB suggested Products section.
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