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  • Primary Antibodies ›
  • LEPRE1 Antibodies

Invitrogen

LEPRE1 Polyclonal Antibody

View all (26) LEPRE1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite LEPRE1 Polyclonal Antibody

  • Antibody Testing Data (2)
LEPRE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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LEPRE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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LEPRE1 Antibody (PA5-53527) in IHC (P)

Immunohistochemical analysis of LEPRE1 in human vulva/anal skin using LEPRE1 Polyclonal Antibody (Product # PA5-53527) shows positivity in fibroblasts. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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LEPRE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
LEPRE1 Antibody in Western Blot (WB)
LEPRE1 Polyclonal Antibody

Product Details

PA5-53527

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LEPRE1. Recombinant protein control fragment (Product #RP-89688).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2643343

Product Specific Information

Immunogen sequence: INKLEKAVAA AHTFFVGNPE HMEMQQNLDY YQTMSGVKEA DFKDLETQPH MQEFRLGVRL YSEEQPQEAV PHLEAALQEY FVAYEECRAL CEGPYDYDGY NYLEYNADLF QAITDHYIQV LNCKQNCVTE LASHP

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.

Target Information

Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro- Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Growth suppressor 1; leprecan; Leprecan-1; leucine proline-enriched proteoglycan (leprecan) 1; Leucine- and proline-enriched proteoglycan 1; procollagen-proline 3-dioxygenase; Prolyl 3-hydroxylase 1

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Gene Aliases: GROS1; LEPRE1; OI8; P3H1; PSEC0109

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UniProt ID: (Human) Q32P28

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Entrez Gene ID: (Human) 64175

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Function(s)
molecular_function iron ion binding collagen binding procollagen-proline 3-dioxygenase activity L-ascorbic acid binding protein complex binding
Process(es)
protein folding negative regulation of cell proliferation protein hydroxylation peptidyl-proline hydroxylation collagen metabolic process regulation of protein secretion protein stabilization oxidation-reduction process bone development chaperone-mediated protein folding negative regulation of post-translational protein modification
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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