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Proteintech
LANCL1 Monoclonal Antibody (2H6E8)
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Product Details
68160-1-IG
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: TKRSITFLCG DAGPLAVAAV LYHKMNNEKQ AEDCITRLIH LNKIDPHAPN EMLYGRIGYI YALLFVNKNF GVEKIPQSHI QQICETILTS GENLARKRNF TAKSPLMYEW YQEYYVGAAH GLAGIYYYLM QPSLQVSQGK LHSLVKPSVD YVCQLKFPSG NYPPCIGDNR DLLVHWCHGA PGVIYMLIQA YKVFREEKYL CDAYQCADVI WQYGLLKKGY GLCHGSAGNA YAFLTLYNLT QDMKYLYRAC KFAEWCLEYG EHGCRTPDTP FSLFEGMAGT IYFLADLLVP TKARFPAFEL
Target Information
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: 40 kDa erythrocyte membrane protein; G protein-coupled receptor 69; G protein-coupled receptor 69A; Glutathione S-transferase LANCL1; LanC (bacterial lantibiotic synthetase component C)-like 1; LanC (bacterial lantibiotic synthetase component); LanC lantibiotic synthetase component C-like 1; LanC-like 1; LanC-like 1(bacterial); LanC-like protein 1; p40
Gene Aliases: AW124738; Gpr69; GPR69A; LANCL1; p40
UniProt ID: (Human) O43813, (Rat) Q9QX69, (Mouse) O89112
Entrez Gene ID: (Human) 10314, (Rat) 114515, (Mouse) 14768
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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