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  • Primary Antibodies ›
  • CD171 (L1CAM) Antibodies

Proteintech

L1CAM Polyclonal Antibody

3 References
View all (90) CD171 (L1CAM) antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite L1CAM Polyclonal Antibody

  • Antibody Testing Data (1)
L1CAM Antibody in Western Blot (WB)
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L1CAM Antibody in Western Blot (WB)
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L1CAM Antibody (20659-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 20659-1-AP (L1CAM antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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L1CAM Antibody in Western Blot (WB)

Product Details

20659-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 1 publication 1 publication

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: antigen identified by monoclonal antibody R1; CD 171; CD171; CD171 molecule; N-CAM L1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; Neural cell adhesion molecule L1; NILE; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM

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Gene Aliases: CAML1; CD171; HSAS; HSAS1; Hyd; L1; L1CAM; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; NCAML1; S10; SPG1

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UniProt ID: (Human) P32004, (Rat) Q05695

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Entrez Gene ID: (Human) 3897, (Mouse) 16728, (Rat) 50687

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Function(s)
integrin binding protein binding PDZ domain binding sialic acid binding identical protein binding protein self-association
Process(es)
chemotaxis cell adhesion nervous system development axon guidance positive regulation of axon extension leukocyte migration homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion cell surface receptor signaling pathway multicellular organism development positive regulation of cell-cell adhesion cell differentiation neuron projection development cell-cell adhesion mediated by integrin homotypic cell-cell adhesion positive regulation of calcium-mediated signaling cellular response to ethanol cellular response to transforming growth factor beta stimulus
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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