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Invitrogen
Kininogen Heavy Chain Monoclonal Antibody (2B5)
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Product Details
MA1-10832
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
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Purification
Storage buffer
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RRID
Product Specific Information
MA1-10832 detects High MW Kininogen, heavy chain, from human samples.
MA1-10832 has been successfully used in ELISA and Western blot applications.
The MA1-10832 immunogen is purified high molecular weight kininogen.
Target Information
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Alpha-2-thiol proteinase inhibitor; bradykinin; Fitzgerald factor; High molecular weight kininogen; HMWK; Kininogen-1; Williams-Fitzgerald-Flaujeac factor
Gene Aliases: BDK; BK; KNG; KNG1
UniProt ID: (Human) P01042
Entrez Gene ID: (Human) 3827
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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