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  • Primary Antibodies ›
  • Kininogen 1 Antibodies

Invitrogen

Kininogen 1 Monoclonal Antibody (09)

View all (21) Kininogen 1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Kininogen 1 Monoclonal Antibody (09)

Kininogen 1 Monoclonal Antibody (09)

Product Details

MA5-30979

Applications
Tested Dilution
Publications

ELISA (ELISA)

1:1,000-1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse

Class

Monoclonal

Type

Antibody

Clone

09

Immunogen

Recombinant Human KNG1/Kininogen 1 Protein (Gln19-Ser644)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2786644

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human KNG1/Kininogen 1.

Target Information

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Alpha-2-thiol proteinase inhibitor; bradykinin; Fitzgerald factor; High molecular weight kininogen; HMWK; Kininogen-1; Williams-Fitzgerald-Flaujeac factor

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Gene Aliases: BDK; BK; KNG; KNG1

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UniProt ID: (Human) P01042

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Entrez Gene ID: (Human) 3827

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Function(s)
cysteine-type endopeptidase inhibitor activity receptor binding protein binding heparin binding zinc ion binding
Process(es)
platelet degranulation smooth muscle contraction inflammatory response negative regulation of cell adhesion positive regulation of cytosolic calcium ion concentration blood coagulation, intrinsic pathway negative regulation of endopeptidase activity negative regulation of blood coagulation positive regulation of urine volume positive regulation of renal sodium excretion vasodilation positive regulation of apoptotic process negative regulation of proteolysis
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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