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Abnova
KIRREL3 Monoclonal Antibody (3A12)
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Product Details
H00084623-M02
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
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Purification
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Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: YSTLSGQGRL YDYGQRFVLG MGSSSIELCE REFQRGSLSD SSSFLDTQCD SSVSSSGKQD GYVQFDKASK ASASSSHHSQ SSSQNSDPSR PLQRRMQTHV
Target Information
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Kin of IRRE-like protein 3; Kin of irregular chiasm-like protein 3; nephrin-like 2; Nephrin-like protein 2
Gene Aliases: KIAA1867; KIRRE; KIRREL3; MRD4; NEPH2; PRO4502; UNQ5923/PRO4502/PRO19814
UniProt ID: (Human) Q8IZU9
Entrez Gene ID: (Human) 84623
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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