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Fabgennix
Junctional Adhesion Molecule 1 Polyclonal Antibody
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Product Details
JAMA-101AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Concentration
Purification
Storage buffer
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Target Information
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: BV11 antigen; CD321; F11 R; F11 receptor/F11R; JAM-1; JAM-A; junction cell adhesion molecule A; junction cell adhesion molecule1; Junctional adhesion molecule 1; Junctional adhesion molecule A; PAM-1; Platelet adhesion molecule 1; Platelet F11 receptor
Gene Aliases: 9130004G24; AA638916; BOS_2618; CD321; ESTM33; F11R; JAM; JAM-1; JAM-A; JAM1; JAMA; JCAM; Jcam1; KAT; Ly106; PAM-1; UNQ264/PRO301
UniProt ID: (Bovine) Q9XT56, (Human) Q9Y624, (Mouse) O88792, (Rat) Q9JHY1
Entrez Gene ID: (Bovine) 281258, (Human) 50848, (Mouse) 16456, (Rat) 116479
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