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  • JAM3 Antibodies

Bioss

JAMC Polyclonal Antibody

View all (11) JAM3 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite JAMC Polyclonal Antibody

  • Antibody Testing Data (2)
JAMC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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JAMC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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JAMC Antibody (BS-11086R) in IHC (P)

Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with JAMC Polyclonal Antibody, Unconjugated (bs-11086R) at 1:400 overnight at 4°C, DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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JAMC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
JAMC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
JAMC Polyclonal Antibody

Product Details

BS-11086R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:400
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human JAMC, amino acids 31-130.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

JAM3 is involved in tight junctions and represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: JAM-2; JAM-3; JAM-C; junction cell adhesion molecule 3; junction cell adhesion molecule C; Junctional adhesion molecule 3; Junctional adhesion molecule C

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Gene Aliases: 1110002N23Rik; JAM-2; JAM-3; JAM-C; JAM3; JAMC; Jcam3; UNQ859/PRO1868

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UniProt ID: (Human) Q9BX67, (Mouse) Q9D8B7, (Rat) Q68FQ2

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Entrez Gene ID: (Human) 83700, (Mouse) 83964, (Rat) 315509

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Function(s)
integrin binding protein binding protein homodimerization activity protein heterodimerization activity
Process(es)
angiogenesis neutrophil homeostasis adaptive immune response myeloid progenitor cell differentiation leukocyte migration involved in inflammatory response cell-matrix adhesion spermatid development transmission of nerve impulse establishment of cell polarity extracellular matrix organization axon regeneration myelination leukocyte migration regulation of neutrophil chemotaxis regulation of actin cytoskeleton organization by cell-cell adhesion cell adhesion spermatogenesis cell migration
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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