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Invitrogen
Importin 4 Polyclonal Antibody
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Product Details
PA5-84656
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Immunogen sequence: VRDNICGALA RLLMASPTRK PEPQVLAALL HALPLKEDLE EWVTIGRLFS FLYQSSPDQV IDVAPELLRI CSLILADNKI PPD
Target Information
Importin-4 is a protein that in humans is encoded by the IPO4 gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Imp4; Imp4b; Importin-4; Importin-4b; Ran-binding protein 4; RanBP4
Gene Aliases: Imp4; IMP4B; IPO4; RANBP4
UniProt ID: (Human) Q8TEX9
Entrez Gene ID: (Human) 79711
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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