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  • ISG20 Antibodies

Abnova

ISG20 Polyclonal Antibody, MaxPab™

View all (8) ISG20 antibodies

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Cite ISG20 Polyclonal Antibody, MaxPab™

  • Antibody Testing Data (1)
ISG20 Antibody in Western Blot (WB)
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ISG20 Antibody in Western Blot (WB)
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ISG20 Antibody (H00003669-D01P) in WB

Western Blot analysis of ISG20 expression in transfected 293T cell line (H00003669-T01) by ISG20 MaxPab polyclonal antibody.

Lane 1: ISG20 transfected lysate(20.40 KDa).
Lane 2: Non-transfected lysate.
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ISG20 Antibody in Western Blot (WB)
ISG20 Polyclonal Antibody, MaxPab™

Product Details

H00003669-D01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ISG20 (NP_002192.2, 1 a.a. approximately 181 a.a) full-length human protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MAGSREVVAM DCEMVGLGPH RESGLARCSL VNVHGAVLYD KFIRPEGEIT DYRTRVSGVT PQHMVGATPF AVARLEILQL LKGKLVVGHD LKHDFQALKE DMSGYTIYDT STDRLLWREA KLDHCRRVSL RVLSERLLHK SIQNSLLGHS SVEDARATME LYQISQRIRA RRGLPRLAVS D

Target Information

Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Estrogen-regulated transcript 45 protein; interferon stimulated exonuclease gene 20kDa; Interferon-stimulated gene 20 kDa protein; Promyelocytic leukemia nuclear body-associated protein ISG20

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Gene Aliases: CD25; HEM45; ISG20

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UniProt ID: (Human) Q96AZ6

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Entrez Gene ID: (Human) 3669

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Function(s)
3'-5'-exoribonuclease activity exonuclease activity single-stranded DNA 3'-5' exodeoxyribonuclease activity exoribonuclease II activity U1 snRNA binding U2 snRNA binding U3 snoRNA binding metal ion binding
Process(es)
DNA catabolic process, exonucleolytic rRNA processing RNA catabolic process cell proliferation response to virus negative regulation of viral genome replication defense response to virus type I interferon signaling pathway RNA phosphodiester bond hydrolysis, exonucleolytic
It has to be done as per old AB suggested Products section.
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