OriGene

INPP5F Monoclonal Antibody (OTI1D4), TrueMAB™

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Datasheet
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Datasheet
Protocols
Questions & Answers
INPP5F Monoclonal Antibody (OTI1D4), TrueMAB™

Product Details

CF809925

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1D4

Immunogen

Full length human recombinant protein of human INPP5F produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EC 3.1.3.36; hSAC2; Inositol polyphosphate 5-phosphatase F; OCRL 1; Phosphatidylinositide phosphatase SAC2; Sac domain-containing inositol phosphatase 2; Sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2

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Gene Aliases: 5830435P03Rik; AI115354; AW561896; cI-27; hSAC2; INPP5F; KIAA0966; mKIAA0966; MSTP007; MSTP047; MSTPO47; SAC2

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UniProt ID: (Human) Q9Y2H2, (Mouse) Q8CDA1

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Entrez Gene ID: (Human) 22876, (Rat) 309008, (Mouse) 101490

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Function(s)
protein binding inositol monophosphate 1-phosphatase activity phosphatidylinositol phosphate 5-phosphatase activity phosphatidylinositol phosphate 4-phosphatase activity protein homodimerization activity inositol monophosphate 3-phosphatase activity inositol monophosphate 4-phosphatase activity molecular_function phosphoric ester hydrolase activity protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity JUN kinase phosphatase activity phosphohistidine phosphatase activity inositol bisphosphate phosphatase activity hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity inositol-1,3,4-trisphosphate 4-phosphatase activity NADP phosphatase activity transmembrane receptor protein phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity inositol-4,5-bisphosphate 5-phosphatase activity 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity phosphatidylinositol-4-phosphate phosphatase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity inositol phosphate phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity inositol-3,4-bisphosphate 4-phosphatase activity inositol-1,3,4-trisphosphate 1-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity IDP phosphatase activity
Process(es)
biological_process cardiac muscle hypertrophy in response to stress phosphatidylinositol catabolic process phosphatidylinositol-mediated signaling regulation of protein kinase B signaling positive regulation of receptor recycling phosphatidylinositol biosynthetic process negative regulation of tyrosine phosphorylation of Stat3 protein phosphatidylinositol dephosphorylation negative regulation of axon regeneration clathrin-mediated endocytosis regulation of cell motility regulation of endocytic recycling
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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