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Bioss
IL17RA/CD217 Polyclonal Antibody
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Product Details
BS-2606R
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CD127; CD217; CDw217; IL-17 receptor A; IL-17RA; Interleukin-17 receptor A; MGC10262
Gene Aliases: AW538159; CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R; IL17RA; VDw217
UniProt ID: (Human) Q96F46, (Mouse) Q60943
Entrez Gene ID: (Human) 23765, (Rat) 312679, (Mouse) 16172
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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