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Invitrogen

IL-7 Recombinant Rabbit Monoclonal Antibody (8X9H8)

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Datasheet
Protocols
Questions & Answers

Cite IL-7 Recombinant Rabbit Monoclonal Antibody (8X9H8)

  • Antibody Testing Data (2)
IL-7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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IL-7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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IL-7 Antibody (MA5-51491) in IHC (P)

Immunohistochemistry analysis of IL-7 in paraffin-embedded rat spleen. Samples were incubated with IL-7 Recombinant monoclonal antibody (Product # MA5-51491) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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IL-7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
IL-7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
IL-7 Recombinant Rabbit Monoclonal Antibody (8X9H8)

Product Details

MA5-51491

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

8X9H8

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 26-177 of human IL7 (NP_000871.1).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093815

Product Specific Information

Immunogen sequence: DCDIEGKDGK QYESVLMVSI DQLLDSMKEI GSNCLNNEFN FFKRHICDAN KEGMFLFRAA RKLRQFLKMN STGDFDLHLL KVSEGTTILL NCTGQVKGRK PAALGEAQPT KSLEENKSLK EQKKLNDLCF LKRLLQEIKT CWNKILMGTK EH

Target Information

Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and natural killer cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD127; H-IL-7; IL-7; IL-7 receptor alpha chain; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; ILN; Interleukin; interleukin 7 receptor alpha chain; Interleukin-7; Interleukin-7 receptor subunit alpha; Interleukin7; M-IL-7

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Gene Aliases: A630026I06Rik; CD127; hlb368; Il-7; IL-7Ralpha; Il7; Il7r

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UniProt ID: (Mouse) P10168, (Mouse) P16872

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Entrez Gene ID: (Mouse) 16196, (Rat) 25647, (Rat) 294797, (Mouse) 16197

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Function(s)
cytokine activity cytokine receptor binding interleukin-7 receptor binding growth factor activity molecular_function cytokine receptor activity
Process(es)
cell morphogenesis negative regulation of T cell mediated cytotoxicity immunoglobulin production biological_process regulation of cell size positive regulation of gene expression cell growth cytokine-mediated signaling pathway T cell differentiation positive regulation of T cell differentiation in thymus B cell proliferation lymph node development homeostasis of number of cells T cell lineage commitment immune response humoral immune response cell-cell signaling organ morphogenesis regulation of gene expression positive regulation of B cell proliferation negative regulation of catalytic activity bone resorption positive regulation of T cell differentiation positive regulation of organ growth homeostasis of number of cells within a tissue negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of apoptotic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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