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  • IL-7 Antibodies

Invitrogen

IL-7 Recombinant Rabbit Monoclonal Antibody (022)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite IL-7 Recombinant Rabbit Monoclonal Antibody (022)

IL-7 Recombinant Rabbit Monoclonal Antibody (022)

Product Details

MA5-30922

Applications
Tested Dilution
Publications

ELISA (ELISA)

1:5,000-1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

022

Immunogen

Recombinant Human IL7/IL-7/Interleukin-7 Protein (Asp26-His177)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2786593

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This antibody has specificity for Human IL7/IL-7/Interleukin-7.

Target Information

Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and natural killer cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD127; CD127 antigen; CDw127; H-IL-7; IL-7; IL-7 receptor subunit alpha; IL-7R subunit alpha; ILN; Interleukin; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin-7; Interleukin-7 receptor subunit alpha; Interleukin7; M-IL-7

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Gene Aliases: CD127; CDW127; IL-7; IL-7R-alpha; IL7; IL7R; IL7RA; ILRA

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UniProt ID: (Human) P13232, (Human) P16871

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Entrez Gene ID: (Human) 3574, (Human) 3575

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Function(s)
cytokine activity interleukin-7 receptor binding protein binding growth factor activity antigen binding interleukin-7 receptor activity
Process(es)
T cell lineage commitment humoral immune response cell-cell signaling positive regulation of cell proliferation organ morphogenesis regulation of gene expression positive regulation of B cell proliferation negative regulation of apoptotic process negative regulation of catalytic activity bone resorption positive regulation of T cell differentiation positive regulation of organ growth homeostasis of number of cells within a tissue negative regulation of extrinsic apoptotic signaling pathway in absence of ligand regulation of DNA recombination cell morphogenesis negative regulation of T cell mediated cytotoxicity immunoglobulin production immune response signal transduction cell surface receptor signaling pathway regulation of cell size positive regulation of gene expression cell growth T cell differentiation positive regulation of T cell differentiation in thymus interleukin-7-mediated signaling pathway B cell proliferation lymph node development homeostasis of number of cells
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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