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Invitrogen
IFN alpha Monoclonal Antibody (RMMA-1)
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FIGURE: 1 / 1
IFN alpha Antibody (221001) in ELISA
Product Details
221001
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
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Purification
Storage buffer
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RRID
Product Specific Information
221001 targets IFN alpha in ELISA and Neutralization applications and shows reactivity with mouse samples. Purity is greater than 95%, and endotoxin level is less than 1 EU/ug.
In neutralization assays, one neutralization unit is the amount of antiserum required to neutralize one unit of mouse IFN alpha to a 50% endpoint. This antibody is expected to work in IP applications, although it has not been fully evaluated for IP.
After receipt, the product may be stored at -20C for short-term use (under 6 months). For long-term storage, the product should be kept at -70C or below for retention of full activity.
IFN alpha has a predicted molecular weight of approximately 19 kDa.
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ifa; IFN alpha 1/13; IFN alpha 1b; IFN α; IFN-alpha-1; IFN-alpha-2; IFNAalphaIFN-alpha-1/13; IFNalpha; IFNα; Interferon alpha 13 (IFNA13); interferon alpha 15; interferon alpha family gene 1; interferon alpha family, gene 2; Interferon alpha leukocyte (IFL); Interferon alpha-1; Interferon alpha-1/13 (IFN-alpha-1/13); interferon alpha-2; Interferon alpha-D (IFN alphaD); Interferon alpha1 (IFNA1); MGC138207; MGC138505; MGC138507; novel interferon alpha (Ifna) family member
Gene Aliases: Gm12597; Ifa1; Ifa2; Ifna1; Ifnaa; MuIFN-alpha-A; OTTMUSG00000007655
UniProt ID: (Mouse) P01572
Entrez Gene ID: (Mouse) 15962, (Mouse) 242517, (Mouse) 15965
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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