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  • CD275 (B7-H2) Antibodies

OriGene

ICOSLG Monoclonal Antibody (OTI2C5), TrueMAB™

View all (62) CD275 (B7-H2) antibodies

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Datasheet
Protocols
Questions & Answers

Cite ICOSLG Monoclonal Antibody (OTI2C5), TrueMAB™

  • Antibody Testing Data (5)
ICOSLG Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ICOSLG Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 5

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ICOSLG Antibody (CF808779) in IHC (P)

Immunohistochemical staining of paraffin-embedded human liver tissue within the normal limits using anti-ICOSLG mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808779)(1:150 {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ICOSLG Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ICOSLG Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ICOSLG Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ICOSLG Antibody in Western Blot (WB)
ICOSLG Antibody in Western Blot (WB)
ICOSLG Monoclonal Antibody (OTI2C5), TrueMAB™

Product Details

CF808779

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OTI2C5

Immunogen

Full length human recombinant protein of human ICOSLG produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: B7 homolog 2; B7 homologue 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD275; ICOS ligand; inducible T-cell co-stimulator ligand; transmembrane protein B7-H2 ICOS ligand

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Gene Aliases: B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; ICOSLG; KIAA0653; LICOS

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UniProt ID: (Human) O75144

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Entrez Gene ID: (Human) 23308

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Function(s)
receptor binding
Process(es)
adaptive immune response defense response hyperosmotic response signal transduction T cell costimulation positive regulation of activated T cell proliferation T cell activation B cell activation
It has to be done as per old AB suggested Products section.
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