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  • Primary Antibodies ›
  • CD275 (B7-H2) Antibodies

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ICOSLG Monoclonal Antibody (3H8)

View all (62) CD275 (B7-H2) antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ICOSLG Monoclonal Antibody (3H8)

ICOSLG Monoclonal Antibody (3H8)

Product Details

H00023308-M05

Applications
Tested Dilution
Publications

ELISA (ELISA)

10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

3H8

Immunogen

ICOSLG (AAH64637.1, 18 a.a. approximately 256 a.a) partial recombinant protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: ADTQEKEVRA MVGSDVELSC ACPEGSRFDL NDVYVYWQTS ESKTVVTYHI PQNSSLENVD SRYRNRALMS PAGMLRGDFS LRLFNVTPQD EQKFHCLVLS QSLGFQEVLS VEVTLHVAAN FSVPVVSAPH SPSQDELTFT CTSINGYPRP NVYWINKTDN SLLDQALQND TVFLNMRGLY DVVSVLRIAR TPSVNIGCCI ENVLLQQNLT VGSQTGNDIG ERDKITENPV STGEKNAAT

Target Information

Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: B7 homolog 2; B7 homologue 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD275; ICOS ligand; inducible T-cell co-stimulator ligand; transmembrane protein B7-H2 ICOS ligand

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Gene Aliases: B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; ICOSLG; KIAA0653; LICOS

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UniProt ID: (Human) O75144

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Entrez Gene ID: (Human) 23308

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Function(s)
receptor binding
Process(es)
adaptive immune response defense response hyperosmotic response signal transduction T cell costimulation positive regulation of activated T cell proliferation T cell activation B cell activation
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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