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  • CD275 (B7-H2) Antibodies

NeoBiotechnologies

ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Monoclonal Antibody (ICOSL/3111)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Monoclonal Antibody (ICOSL/3111)

  • Antibody Testing Data (6)
ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody in Immunocytochemistry (ICC/IF)
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ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 6

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ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody (23308-MSM1-P0) in ICC/IF

Immunofluorescence staining of U937 cells using ICOS-L Mouse Monoclonal Antibody (ICOSL/3111) followed by goat anti-Mouse IgG conjugated to CF488 (green). Nuclei are stained with Reddot. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody in Immunocytochemistry (ICC/IF)
ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody in Flow Cytometry (Flow)
ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody in Peptide array (ARRAY)
ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody in SDS-PAGE (SDS-PAGE)
ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Monoclonal Antibody (ICOSL/3111)

Product Details

23308-MSM1-P0

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-

Immunocytochemistry (ICC/IF)

1-2 µg/mL
-

Flow Cytometry (Flow)

1-2 µg/10^6 cells
-

ELISA (ELISA)

Assay-dependent
-

Peptide Array (Array)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

ICOSL/3111

Immunogen

Recombinant fragment of human ICOSLG (B7RP-1) protein (around aa 23-149).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: B7 homolog 2; B7 homologue 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD275; ICOS ligand; inducible T-cell co-stimulator ligand; transmembrane protein B7-H2 ICOS ligand

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Gene Aliases: B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; ICOSLG; KIAA0653; LICOS

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UniProt ID: (Human) O75144

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Entrez Gene ID: (Human) 23308

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Function(s)
receptor binding
Process(es)
adaptive immune response defense response hyperosmotic response signal transduction T cell costimulation positive regulation of activated T cell proliferation T cell activation B cell activation
It has to be done as per old AB suggested Products section.
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