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  • Primary Antibodies ›
  • HuD Antibodies

Invitrogen

HuD Polyclonal Antibody

View all (11) HuD antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite HuD Polyclonal Antibody

  • Antibody Testing Data (1)
HuD Antibody in Immunocytochemistry (ICC/IF)
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HuD Antibody in Immunocytochemistry (ICC/IF)
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HuD Antibody (PA5-83642) in ICC/IF

Immunofluorecent analysis of HuD in human cell line U-251 MG using HuD Polyclonal Antibody (Product # PA5-83642). Staining shows localization to nucleoplasm and vesicles. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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HuD Antibody in Immunocytochemistry (ICC/IF)

Product Details

PA5-83642

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ELAVL4. Recombinant protein control fragment (Product #RP-108358).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790795

Product Specific Information

Immunogen sequence: VMIISTMEPQ VSNGPTSNTS NGPSSNNRNC PSPMQTGATT DDSK

Target Information

HuD, otherwise known as ELAV-like protein 4 or PNEM, is a protein that in humans is encoded by the ELAVL4 gene. This human gene is located at 1p34 by in situ hybridization. The HuD/ELAVL4 protein is an RNA-binding protein. ELAVL4 has specificity for 3-prime uridylate-rich untranslated regions of growth factor mRNAs. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the, half-life of the transcript is increased. Additionally, HuD is important in neurons during brain development and plasticity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV-like protein 4; Hu antigen D; Hu-antigen D; HuD; Paraneoplastic encephalomyelitis antigen HuD

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Gene Aliases: ELAVL4; HUD; PNEM

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UniProt ID: (Human) P26378

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Entrez Gene ID: (Human) 1996

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Function(s)
nucleotide binding RNA binding mRNA 3'-UTR binding AU-rich element binding
Process(es)
RNA processing mRNA processing
It has to be done as per old AB suggested Products section.
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