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Invitrogen
HuD Polyclonal Antibody
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FIGURE: 1 / 4
HuD Antibody (PA5-116521) in IHC (P)
Product Details
PA5-116521
Species Reactivity
Host/Isotype
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Immunogen
Conjugate
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Product Specific Information
Positive Samples: Mouse brain, Rat brain
Immunogen sequence: MVMIISTMEP QVSNGPTSNT SNGPSSNNRN CPSPMQTGAT TDDSKTNLIV NYLPQNMTQE EFRSLFGSIG EIESCKLVRD KITGQSLGYG FVNYIDPKDA
Target Information
HuD, otherwise known as ELAV-like protein 4 or PNEM, is a protein that in humans is encoded by the ELAVL4 gene. This human gene is located at 1p34 by in situ hybridization. The HuD/ELAVL4 protein is an RNA-binding protein. ELAVL4 has specificity for 3-prime uridylate-rich untranslated regions of growth factor mRNAs. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the, half-life of the transcript is increased. Additionally, HuD is important in neurons during brain development and plasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV-like protein 4; HU-antigen D; HuD; Paraneoplastic encephalomyelitis antigen HuD; RNA-binding protein HUD3
Gene Aliases: Elav; Elavl4; HuD; PNEM; r-HuD; RGD1561943
UniProt ID: (Mouse) Q61701, (Rat) O09032
Entrez Gene ID: (Mouse) 15572, (Rat) 432358
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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