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  • HYAL1 Antibodies

Invitrogen

HYAL1 Polyclonal Antibody

View all (14) HYAL1 antibodies

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Questions & Answers

Cite HYAL1 Polyclonal Antibody

  • Antibody Testing Data (1)
HYAL1 Antibody in Western Blot (WB)
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HYAL1 Antibody in Western Blot (WB)
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HYAL1 Antibody (PA5-79421) in WB

Western blot analysis of HYAL1 in Lane 1: NRK cell lysate, Lane 2: mouse liver tissue lysate, Lane 3: mouse kidney tissue lysate, Lane 4: SP2/0 cell lysate. Sample was incubated with HYAL1 polyclonal antibody (Product # PA5-79421). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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HYAL1 Antibody in Western Blot (WB)
HYAL1 Polyclonal Antibody

Product Details

PA5-79421

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.5 µg/mL
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse HYAL1 (434-450aa LKDRAQMAMKFRCRCYR).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5mg BSA

Contains

0.05mg sodium azide, 0.05mg thimerosal

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2746537

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - WB: NRK Cell, Mouse Liver Tissue, Mouse Kidney Tissue, SP2/0 Cell.

Target Information

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Hyal-1; Hyaluronidase; hyaluronidase 1; Hyaluronidase-1; Hyaluronoglucosaminidase-1

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Gene Aliases: Hya1; Hyal-1; Hyal1

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UniProt ID: (Mouse) Q91ZJ9

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Entrez Gene ID: (Mouse) 15586

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Function(s)
virus receptor activity catalytic activity hyalurononglucosaminidase activity transcription factor binding hydrolase activity hydrolase activity, acting on glycosyl bonds hyaluronan synthase activity
Process(es)
response to reactive oxygen species carbohydrate metabolic process inflammatory response metabolic process response to virus positive regulation of epithelial cell migration hyaluronan metabolic process hyaluronan biosynthetic process hyaluronan catabolic process positive regulation of cell growth negative regulation of cell growth cellular response to platelet-derived growth factor stimulus cellular response to fibroblast growth factor stimulus positive regulation of angiogenesis positive regulation of cell adhesion positive regulation of growth response to antibiotic positive regulation of epithelial cell proliferation embryonic skeletal joint morphogenesis cellular response to interleukin-1 cellular response to pH cellular response to UV-B positive regulation of hyaluranon cable assembly
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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