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Invitrogen
HSPA4 Polyclonal Antibody
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FIGURE: 1 / 7
HSPA4 Antibody (PA5-29484) in ICC/IF
Product Details
PA5-29484
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, U87-MG, SK-N-SH, IMR32, SK-N-AS.
Predicted reactivity: Mouse (97%), Rat (96%), Xenopus laevis (87%), Dog (98%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The HSP 70 family is composed of four highly conserved proteins: HSP 70, HSC 70, GRP 75 and GRP 78. HSP 70 expression is strongly induced in response to heat stress. HSP 70 and HSC 70 play key roles in the cytosolic endoplasmic reticulum and mitochondrial import machinery and are found in both the cytosol and nucleus of mammalian cells. GRP 78 is localized in the endoplasmic reticulum, where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains. GRP 75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains of both nuclear and mitochondrial origin. It has been postulated that members of the HSP 70 family act as force-generating motors, relying on the hydrolysis of ATP for their activity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein Li 5a; Heat shock 70 kDa protein 4; Heat shock 70-related protein APG-2; heat shock 70kD protein 4; heat shock 70kDa protein 4; Heat shock protein; Heat shock protein family H member 2; heat shock protein, 110 kDa; hsp70 RY; HSP70RY; Ischemia responsive 94 kDa protein
Gene Aliases: APG-2; APG2; HEL-S-5a; HS24/P52; Hsp110; Hsp70; hsp70RY; HSPA4; HSPH2; Irp94; RY
UniProt ID: (Human) P34932, (Rat) O88600
Entrez Gene ID: (Human) 3308, (Rat) 266759
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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