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  • HRG Antibodies

Proteintech

HRG Polyclonal Antibody

2 References
View all (14) HRG antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite HRG Polyclonal Antibody

  • Antibody Testing Data (2)
HRG Antibody in Western Blot (WB)
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HRG Antibody in Western Blot (WB)
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FIGURE: 1 / 2

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HRG Antibody (26252-1-AP) in WB

human plasma were subjected to SDS PAGE followed by western blot with (Product # 26252-1-AP) (HRG antibody) at dilution of 1:2,0000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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HRG Antibody in Western Blot (WB)
HRG Antibody in Western Blot (WB)
HRG Polyclonal Antibody

Product Details

26252-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Miscellaneous PubMed (MISC)

-
View 1 publication 1 publication

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HRG Fusion Protein Ag16278 (19-368 aa encoded by BC069574)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.36 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VSPTDCSAV EPEAEKALDL INKRRRDGYL FQLLRIADAH LDRVENTTVY YLVLDVQESD CSVLSRKYWN DCEPPDSRRP SEIVIGQCKV IATRHSHESQ DLRVIDFNCT TSSVSSALAN TKDSPVLIDF FEDTERYRKQ ANKALEKYKE ENDDFASFRV DRIERVARVR GGEGTGYFVD FSVRNCPRHH FPRHPNVFGF CRADLFYDVE ALDLESPKNL VINCEVFDPQ EHENINGVPP HLGHPFHWGG HERSSTTKPP FKPHGSRDHH HPHKPHEHGP PPPPDERDHS HGPPLPQGPP PLLPMSCSSC QHATFGTNGA QRHSHNNNSS DLHPHKHHSH EQHPHGHHPH A (19-368 aa encoded by BC069574)

Target Information

HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: DKFZp779H1622; Histidine-proline-rich glycoprotein; Histidine-rich glycoprotein; HPRG

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Gene Aliases: HPRG; HRG; HRGP; THPH11

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UniProt ID: (Human) P04196

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Entrez Gene ID: (Human) 3273

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Function(s)
serine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity receptor binding protein binding heparin binding zinc ion binding immunoglobulin binding heme binding heparan sulfate proteoglycan binding metal ion binding
Process(es)
angiogenesis platelet degranulation positive regulation of immune response to tumor cell chemotaxis negative regulation of cell adhesion negative regulation of cell proliferation regulation of gene expression regulation of platelet activation negative regulation of lamellipodium assembly negative regulation of endopeptidase activity heme transport negative regulation of angiogenesis platelet activation regulation of blood coagulation negative regulation of cell growth regulation of actin cytoskeleton organization negative regulation of cell adhesion mediated by integrin fibrinolysis positive regulation of apoptotic process regulation of protein complex assembly negative regulation of blood vessel endothelial cell migration regulation of peptidyl-tyrosine phosphorylation defense response to fungus positive regulation of focal adhesion assembly negative regulation of fibrinolysis negative regulation of vascular endothelial growth factor signaling pathway positive regulation of blood vessel remodeling negative regulation of endothelial cell chemotaxis
It has to be done as per old AB suggested Products section.
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