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  • HMGCS2 Antibodies

Invitrogen

HMGCS2 Recombinant Rabbit Monoclonal Antibody (JE54-76)

View all (11) HMGCS2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite HMGCS2 Recombinant Rabbit Monoclonal Antibody (JE54-76)

  • Antibody Testing Data (4)
HMGCS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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HMGCS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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HMGCS2 Antibody (MA5-44837) in IHC (P)

Immunohistochemistry analysis of HMGCS2 in paraffin-embedded human kidney tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with HMGCS2 Monoclonal antibody (Product # MA5-44837) using a dilution of 1:50 for 30 minutes at ... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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HMGCS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
HMGCS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
HMGCS2 Antibody in Western Blot (WB)
HMGCS2 Antibody in Western Blot (WB)
HMGCS2 Recombinant Rabbit Monoclonal Antibody (JE54-76)

Product Details

MA5-44837

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

JE54-76

Immunogen

Synthetic peptide within human HMGCS2 aa 459-508/508.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2931294

Target Information

The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 3-hydroxy-3-methylglutary-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); HMG-CoA synthase; hydroxymethylglutaryl-CoA synthase 2; Hydroxymethylglutaryl-CoA synthase, mitochondrial; testicular tissue protein Li 88

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Gene Aliases: 1300002P16; Hmgcs1; HMGCS2; mHS; Mt3h3mg

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UniProt ID: (Human) P54868, (Rat) P22791, (Mouse) P54869

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Entrez Gene ID: (Human) 3158, (Rat) 24450, (Mouse) 15360

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Function(s)
hydroxymethylglutaryl-CoA synthase activity catalytic activity transferase activity
Process(es)
kidney development liver development cholesterol biosynthetic process brain development midgut development response to nutrient isoprenoid biosynthetic process response to temperature stimulus response to bacterium response to metal ion response to organic cyclic compound lung development response to insulin cellular response to insulin stimulus cellular response to hormone stimulus multicellular organismal response to stress response to testosterone response to glucagon response to triglyceride response to monosaccharide response to prostaglandin F response to drug response to starvation response to peptide hormone response to ethanol ketone body biosynthetic process response to glucocorticoid response to cAMP response to growth hormone adipose tissue development response to fatty acid response to linoleic acid cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to glucocorticoid stimulus cellular response to fatty acid cellular response to organic cyclic compound lipid metabolic process steroid biosynthetic process metabolic process steroid metabolic process cholesterol metabolic process sterol biosynthetic process
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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