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  • Primary Antibodies ›
  • HMGCS2 Antibodies

Invitrogen

HMGCS2 Polyclonal Antibody

View all (11) HMGCS2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite HMGCS2 Polyclonal Antibody

  • Antibody Testing Data (1)
HMGCS2 Antibody in Western Blot (WB)
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HMGCS2 Antibody in Western Blot (WB)
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HMGCS2 Antibody (PA5-42023) in WB

Western blot analysis of human Jurkat cell lysate using an anti-HMGCS2 polyclonal antibody (Product # PA5-42023). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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HMGCS2 Antibody in Western Blot (WB)
HMGCS2 Polyclonal Antibody

Product Details

PA5-42023

Applications
Tested Dilution
Publications

Western Blot (WB)

5 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human HMGCS2 (aa 51-100).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608516

Product Specific Information

Peptide sequence: PKDVGILALE VYFPAQYVDQ TDLEKYNNVE AGKYTVGLGQ TRMGFCSVQE

Sequence homology: Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Target Information

The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); HMG-CoA synthase; Hydroxymethylglutaryl-CoA synthase, mitochondrial; testicular tissue protein Li 88

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Gene Aliases: HMGCS2

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UniProt ID: (Human) P54868

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Entrez Gene ID: (Human) 3158

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Function(s)
hydroxymethylglutaryl-CoA synthase activity
Process(es)
kidney development liver development cholesterol biosynthetic process brain development midgut development response to nutrient isoprenoid biosynthetic process response to temperature stimulus response to metal ion lung development cellular response to insulin stimulus multicellular organismal response to stress response to testosterone response to glucagon response to triglyceride response to monosaccharide response to prostaglandin F response to drug response to starvation response to ethanol ketone body biosynthetic process response to cAMP response to growth hormone adipose tissue development response to linoleic acid cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to glucocorticoid stimulus cellular response to fatty acid
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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