Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
HLCS Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
14046-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: SYVSEVEIT PSCIPVVTNM EAFSSEHFNL EIYRQNLQTK QLGKVILFAE VTPTTMRLLD GLMFQTPQEM GLIVIAARQT EGKGRGGNVW LSPVGCALST LLISIPLRSQ LGQRIPFVQH LMSVAVVEAV RSIPEYQDIN LRVKWPNDIY YSDLMKIGGV LVNSTLMGET FYILIGCGFN VTNSNPTICI NDLITEYNKQ HKAELKPLRA DYLIARVVTV LEKLIKEFQD KGPNSVLPLY YRYWVHSGQQ VHLGSAEGPK VSIVGLDDSG FLQVHQEGGE VVTVHPDGNS FDMLRNLILP KRR (425-726 aa encoded by BC060787)
Target Information
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Biotin apo-protein ligase; biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase; biotin--[acetyl-CoA-carboxylase] ligase; biotin--[methylcrotonoyl-CoA-carboxylase] ligase; biotin--[methylmalonyl-CoA-carboxytransferase] ligase; Biotin--protein ligase; holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase); holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)
Gene Aliases: 410I21.SP6; D16Jhu34; HCS; HLCS; RGD1565360
UniProt ID: (Human) P50747, (Mouse) Q920N2
Entrez Gene ID: (Human) 3141, (Rat) 288240, (Mouse) 110948
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support