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  • Primary Antibodies ›
  • HEPH Antibodies

Invitrogen

HEPH Polyclonal Antibody

View all (7) HEPH antibodies

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Datasheet
Protocols
Questions & Answers

Cite HEPH Polyclonal Antibody

  • Antibody Testing Data (3)
HEPH Antibody in Western Blot (WB)
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HEPH Antibody in Western Blot (WB)
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HEPH Antibody (PA5-145431) in WB

Western blot analysis of HEPH in Human Lung lysate. Samples were incubated with HEPH polyclonal antibody (Product # PA5-145431) using a dilution of 2 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG secondary antibody at a dilution of 0.2 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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HEPH Antibody in Western Blot (WB)
HEPH Antibody in Western Blot (WB)
HEPH Antibody in Western Blot (WB)
HEPH Polyclonal Antibody

Product Details

PA5-145431

Applications
Tested Dilution
Publications

Western Blot (WB)

0.01-2 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human HEPH protein, Ala24-Cys366 (Accession #Q9BQS7)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093581

Target Information

B1AJX8(HEPH) is similar to an iron transport protein found in mouse. The mouse protein is similar to ceruloplasmin, a serum multi-copper ferroxidase, and is thought to be a membrane-bound protein responsible for transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system. In mouse, defects in this gene can lead to severe microcytic anemia. Three transcript variants encoding different isoforms have been described for this gene. The protein encoded by this gene is similar to an iron transport protein found in mouse. The mouse protein is similar to ceruloplasmin, a serum multi-copper ferroxidase, and is thought to be a membrane-bound protein responsible for transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system. In mouse, defects in this gene can lead to severe microcytic anemia. Two transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: haphaestin; Hephaestin; Hp; sex linked anemia

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Gene Aliases: C130006F04Rik; CPL; HEPH; KIAA0698; mKIAA0698; sla; UNQ2562/PRO6242

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UniProt ID: (Human) Q9BQS7, (Mouse) Q9Z0Z4

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Entrez Gene ID: (Human) 9843, (Mouse) 15203

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Function(s)
ferroxidase activity copper ion binding ferrous iron binding N-ethylmaleimide reductase activity oxidoreductase activity reduced coenzyme F420 dehydrogenase activity sulfur oxygenase reductase activity malolactic enzyme activity NADPH:sulfur oxidoreductase activity metal ion binding epoxyqueuosine reductase activity
Process(es)
copper ion transport iron ion transport cellular iron ion homeostasis oxidation-reduction process transport ion transport erythrocyte differentiation iron ion homeostasis
It has to be done as per old AB suggested Products section.
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