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NeoBiotechnologies
Glucose 6-Phosphate Isomerase Monoclonal Antibody (CPTC-GPI-1)
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FIGURE: 1 / 5
Glucose 6-Phosphate Isomerase Antibody (2821-MSM1-P1ABX) in ICC/IF
Product Details
2821-MSM1-P1ABX
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Storage conditions
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Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Target Information
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: AMF; Autocrine motility factor; glucose phosphate isomerase; Glucose-6-phosphate isomerase; GPI; hexose monophosphate isomerase; hexosephosphate isomerase; Neuroleukin; NLK; oxoisomerase; PGI; PHI; Phosphoglucose isomerase; phosphohexomutase; Phosphohexose isomerase; phosphosaccharomutase; SA-36; sperm antigen; Sperm antigen 36; sperm antigen-36
Gene Aliases: AMF; GNPI; GPI; NLK; PGI; PHI; SA-36; SA36
UniProt ID: (Human) P06744
Entrez Gene ID: (Human) 2821
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